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About Epilepsy: Diagnosing Epilepsy
DIAGNOSING EPILEPSY
Diagnosing Epilepsy involves a series of tests and procedures. Physicians will
initially take a person's medical history including their family's health history.
Health care professionals will need to know when the seizures started and a
detailed description of the seizures; what a person was doing before the
seizure and how long it lasted are examples of things to record and pass along
to your Doctor. Diagnosis of a seizure disorder is based on the following
considerations and diagnostic tests.
DIAGNOSTIC TESTS
CAT Scan
Computerized Axial Tomography, also known as CT (Computed Tomography)
imaging, is a safe and non-invasive procedure which uses low radiation X-rays
to create a computer-generated, three-dimensional image of the brain. It
provides detailed information about the structure of the brain by using a series
of X-ray beams passing through the head to create cross-sectional images of
the brain. These may reveal abnormalities (blood clots, cysts, tumours, scar
tissue, etc.) in the skull or brain which may be related to seizures. This allows
physicians to examine this structure, section by section, as the test is being
conducted. The CAT scan helps to point to where a person's seizures originate.
EEG
An electroencephalogram is a non-invasive test which detects and records
electrical impulses on the surface of the brain. These impulses are transmitted
from small metal discs, placed on the person's scalp, through wires which are
connected to an electroencephalograph - the instrument used to register this
activity and record it on graph paper or on a computer screen.
This safe and painless procedure will not affect you in any way.
An EEG is used by a neurologist to determine whether there are any irregular
electrical activities occurring in the brain which may produce seizures. It can
help identify the location, severity, and type of seizure disorder.
An abnormal EEG does not diagnose epilepsy nor does a normal EEG reading
exclude it.
MEG/MSI
Magnetoencephalography, also called Magnetic Source Imaging, is a non-
invasive scanning technique which provides information about function of the
brain. It is a safe and painless procedure that detects small biomagnetic signals
produced by the brain, recording magnetic fields over the surface of the head.
These signals provide information about the location of active brain areas. This
technique allows doctors to investigate how different areas of the brain interact
with one another.
MEG can help to identify brain zones which emit abnormal electric currents
associated with epilepsy; "see" the magnetic fields associated with sensory
areas of the brain by stimulating the senses during MEG recording sessions;
view the brain zones which control language by having the patient perform
linguistic tasks during MEG; and, identify the brain zones associated with
learning and memory by having the patient perform cognitive tasks during
MEG. It is useful in planning surgical treatment of epilepsy and for pre-surgical
functional mapping of the brain. It quickly provides high resolution images of
the brain, used to compare function in relationship to behaviour.
MRI
Magnetic Resonance Imaging is a safe and non-invasive scanning technique
that uses a magnetic field, radio waves, and a computer to produce two or
three dimensional images of the brain. This detailed picture of brain structures
helps physicians locate possible causes of seizures and identify areas that may
generate seizures. No X-rays or radioactive materials are used, therefore this
procedure is not known to be harmful.
An MRI offers doctors the best chance of finding the source of seizures.
Because seizures can arise from scar tissue in the brain, an MRI can show
scar tissue and allow doctors to determine the nature of it. The images
produced from the MRI are extremely precise. The information provided by MRI
is valuable in the diagnosis and treatment of individuals with epilepsy and in
determining whether surgery would be beneficial.
MRSI
Magnetic Resonance Spectroscopic Imaging is similar to MRI except that, while
MRI looks at the signals detected from the protons of water in the body, MRSI
looks at the signals detected from other proton-containing metabolites.
PET
Positron Emission Tomography is a scanning technique which detects chemical
and physiological changes related to metabolism. It produces 3-dimensional
images of blood flow, chemical reactions and muscular activity in the body as
they occur. It measures the intensity of the use (metabolization) of glucose,
oxygen or other substances in the brain.
This allows the neurologist to study the function of the brain. By measuring
areas of blood flow and metabolism, the PET scan is used to locate the site
from which a seizure originates.
The PET scan provides information about metabolic activities, chemistry or
blood flow by detecting how quickly tissues absorb radioactive isotopes. A
small amount of radioactive substance is injected into the body. When this
substance reaches the brain during the scan, a computer uses the recorded
signals to create images of specific brain functions. A functional image of brain
activity is important because functional changes are often present before
structural changes in tissues.
The information provided by a PET scan is valuable in the diagnosis of seizure
type and in the evaluation of a potential candidate for surgery. PET images may
therefore demonstrate pathological changes long before they would be made
evident by other scanning techniques.
Functional MRI
Similar to PET, a functional MRI provides information about active brain tissue
function and blood delivery. However, it is more precise in temporal and spatial
resolution. It is an ideal tool in pre-operative planning because it can reveal the
exact location of the seizure area.
SPECT
Single Photon Emission Computed Tomography is a functional imaging
technique which creates 3-dimensional images of the brain on a computer,
allowing physicians to visualize blood flow through different areas of the brain.
Individuals with epilepsy often have changes in blood flow to specific areas of
the brain when a seizure begins. By measuring blood flow, the SPECT scan
may help to identify where seizures originate. This test provides information
about how well the various regions of the brain are functioning by measuring
relative cerebral blood flow. This information helps your physician to more
accurately diagnose the type of seizure, locate the site where a seizure
originates, and evaluate a potential candidate for surgery.
The radiation exposure from a brain scan is small. It is in the range of 1 to 3
times your annual exposure to natural background radiation.
Information provided is not intended to replace any medical advice provided by your
physician or neurologist. It is intended to supply general information on epilepsy and
seizures. For further medical information or specific diagnostic questions, please refer
your concerns to your physician or neurologist.
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